Anandamide

The word “anandamide” originates from the sanskrit “ananda,” which roughly translates to “bliss” or “joy,” an indication of the cannabinoid’s properties as a mood enhancer. Also called N-arachidonoylethanolamine (AEA), anandamide interacts with the body’s CB receptors similarly to cannabinoids like THC. It’s a neurotransmitter and cannabinoid-receptor binding agent that functions as a signal messenger for CB receptors located in the body.

Esteemed chemist Dr. Raphael Mechoulam, known for his groundbreaking pharmacological research on cannabinoids (including the discovery of delta-9-THC in the 1960s), first discovered anandamide when attempting to answer the question: Why do our bodies contain cannabinoid receptors that are capable of binding with external or cannabinoids such as THC or CBD?

Our bodies create anandamide on-demand, to be used when needed to maintain homeostasis. Anandamide does this by helping to regulate inflammation and neuron signaling. As it is created, it binds primarily with our cannabinoid receptors CB1 and CB2 just as a cannabinoids such as THC would upon ingestion. Anandamide’s molecular fragility lends itself to be broken down quite easily. It doesn’t stick around in the body for long.

read more at https://www.leafly.com/news/science-tech/meet-bliss-molecule-anandamide-cannabinoid

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